Small Intestinal Bacterial Overgrowth Affects the Responsiveness to Colchicine in Familial Mediterranean Fever
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Small Intestinal Bacterial Overgrowth Affects the Responsiveness to Colchicine in Familial Mediterranean Fever
Objective Familial Mediterranean fever (FMF) is an autosomal recessive disease due to a MEFV gene mutation. Since Helicobacter pylori infection has been described to increase the severity and frequency of FMF attacks, we evaluate if overgrowth of small intestinal bacterial (SIBO), associated with a release of bacterial products, can affect the response to colchicine in FMF patients poorly respo...
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Small intestinal bacterial overgrowth (SIBO) is characterized by an overgrowth of various types of bacteria in the small intestine, bacteria which are largely only found in the colon. SIBO was initially thought of as a rare condition; however, it is now recognized as a more prevalent digestive disorder than previously acknowledged. A meta-analysis has shown the prevalence of SIBO to be approxim...
متن کاملSmall intestinal bacterial overgrowth.
Despite the current increase in interest in the role of the microbiota in health and disease and the recognition, for over 50 years, that an excess of colonic-type flora in the small intestine could lead to a malabsorption syndrome, small intestinal overgrowth remains poorly defined. This lack of clarity owes much to the difficulties that arise in attempting to arrive at consensus with regard t...
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The importance of friendly bacteria in the large intestine is becoming clearer. In fact, the recent focus of research on the beneficial bacteria in the large intestine and their relationship with health outcomes has been hard to ignore. Study after study indicates that the gut microbiome is intricately related to our health and well-being. However, the extent of the benefits of the gut bacteria...
متن کاملIntroduction to Small Intestinal Bacterial Overgrowth
27 INTRODUCTION TO SMALL INTESTINAL BACTERIAL OVERGROWTH Small intestinal bacterial overgrowth (SIBO) is an often-neglected mechanism for impaired nutrition. This review will examine the pathogenesis of SIBO and the multifaceted impact of this condition on the nutritional status of the human host. Normally, only small numbers of bacteria are found in the small intestine when compared with that ...
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ژورنال
عنوان ژورنال: Mediators of Inflammation
سال: 2017
ISSN: 0962-9351,1466-1861
DOI: 10.1155/2017/7461426